Xi’an Nuojia Bio-tech Co., Ltd. is an innovative manufacturer which is specialized in providing customers with full line of herbal extracts, Natural Active Ingredients, Standardized Botanical Extracts, Water-soluble Products. Our products can be widely used in dietary supplements, functional food, sports nutrients, functional Beverage, Cosmetics etc. Most of our products enjoy great reputation in North American, European, Middle East, and South Africa.

Now I recommend you one of our featured products as follows:

If you are interested in it, please do not hesitate to contact us.

Peter Zhang
Marketing manager

Xi’an Nuojia Bio-tech. Co., Ltd.

E-mail: info@nuojiabio.com

nuojiabio@gmail.com

Tel: 00-86-29-89388701

Fax: 00-86-29-89383287

Cell phone: 00-86-15353576829

#

Add: Tsinghua Science and Technology Park, Xi’an High-tech district, Xi’an, China

Number: NJF-011

Common name: Oleocanthal

CAS NO.: 289030-99-5

Molecular Formula: C17-H20-O5

Molecular Weight: 304.34

Structure:

Specification: 99%
Test method: HPLC

Packing: 5 gram/ bag
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
Applications :

What is oleocanthal

Oleocanthal is a phenylethanoid, a type of natural phenolic compound found in extra-virgin olive oil. It appears to be responsible for the burning sensation that occurs in the back of the throat when consuming such oil. Oleocanthal is a tyrosol ester and its chemical structure is related to oleuropein, also found in olive oil.

Health Benefits of Oleocanthal

1.       Anti-inflammatory

Oleocanthal has been found to have anti-inflammatory and antioxidant properties in vitro. Similar to classical non-steroidal anti-inflammatory drugs, it is a non-selective inhibitor of cyclooxygenase (COX). 50 g (more than three and a half tablespoons) of a typical extra virgin olive oil per day contains an amount of oleocanthal with similar in vitro anti-inflammatory effect as 1/10 of the adult ibuprofen dose. It is therefore suggested that long-term consumption of small quantities may be responsible in part for the low incidence of heart disease and Alzheimer's disease associated with a Mediterranean diet.

2.       Alzheimer’s disease

Oleocanthal can reduce the accumulation of β-amyloid proteins involved in Alzheimer's Disease, via up-regulation ofP-glycoprotein and LRP1

3.       Anticancer

Oleocanthal is capable of killing a variety of human cancer cells in vitro while leaving healthy cells unharmed. While apoptosis requires between 16 and 24 hours, oleocanthal operated within 30 minutes to one hour. Oleocanthal pierces cancer cells' lysosomes, the containers that store the cell's waste products, releasing enzymes that kill the cell. In healthy cells, the application of oleocanthal caused a temporary halt in their life cycles, but after 24 hours they returned to normal.

Oleocanthal inhibits the enzymatic activity of mammalian target of rapamycin (mTOR) with an IC₅₀ value of 708 nM. Oleocanthal inhibits the growth of several breast cancer cell lines at low micromolar concentration in a dose-dependent manner. Oleocanthal treatment caused a marked downregulation of phosphorylated mTOR in metastatic breast cancer cell line (MDA-MB-231). These results strongly indicate that mTOR inhibition is at least one of the factors of the reported anticancer and neuroprotective properties of oleocanthal.

Xi’an Nuojia Bio-tech Co., Ltd. is an innovative manufacturer which is specialized in providing customers with full line of herbal extracts, Natural Active Ingredients, Standardized Botanical Extracts, Water-soluble Products. Our products can be widely used in dietary supplements, functional food, sports nutrients, functional Beverage, Cosmetics etc. Most of our products enjoy great reputation in North American, European, Middle East, and South Africa.

Now I recommend you one of our featured products as follows:

If you are interested in it, please do not hesitate to contact us.

Peter Zhang
Marketing manager

Xi’an Nuojia Bio-tech. Co., Ltd.

E-mail: info@nuojiabio.com

nuojiabio@gmail.com

Tel: 00-86-29-89388701

Fax: 00-86-29-89383287

Cell phone: 00-86-15353576829

#

Add: Tsinghua Science and Technology Park, Xi’an High-tech district, Xi’an, China

nuojiabio at gmail dot com

Number: NJF-011

Common name: Oleocanthal

CAS NO.: 289030-99-5

Molecular Formula: C17-H20-O5

Molecular Weight: 304.34

Structure:

Specification: 99%
Test method: HPLC

Packing: 5 gram/ bag
Storage: Store in cool and dry place and keep away from strong direct light and heat
Shelf Life: Two years when properly stored
Applications :

What is oleocanthal

Oleocanthal is a phenylethanoid, a type of natural phenolic compound found in extra-virgin olive oil. It appears to be responsible for the burning sensation that occurs in the back of the throat when consuming such oil. Oleocanthal is a tyrosol ester and its chemical structure is related to oleuropein, also found in olive oil.

Health Benefits of Oleocanthal

1.       Anti-inflammatory

Oleocanthal has been found to have anti-inflammatory and antioxidant properties in vitro. Similar to classical non-steroidal anti-inflammatory drugs, it is a non-selective inhibitor of cyclooxygenase (COX). 50 g (more than three and a half tablespoons) of a typical extra virgin olive oil per day contains an amount of oleocanthal with similar in vitro anti-inflammatory effect as 1/10 of the adult ibuprofen dose. It is therefore suggested that long-term consumption of small quantities may be responsible in part for the low incidence of heart disease and Alzheimer's disease associated with a Mediterranean diet.

2.       Alzheimer’s disease

Oleocanthal can reduce the accumulation of β-amyloid proteins involved in Alzheimer's Disease, via up-regulation ofP-glycoprotein and LRP1

3.       Anticancer

Oleocanthal is capable of killing a variety of human cancer cells in vitro while leaving healthy cells unharmed. While apoptosis requires between 16 and 24 hours, oleocanthal operated within 30 minutes to one hour. Oleocanthal pierces cancer cells' lysosomes, the containers that store the cell's waste products, releasing enzymes that kill the cell. In healthy cells, the application of oleocanthal caused a temporary halt in their life cycles, but after 24 hours they returned to normal.

Oleocanthal inhibits the enzymatic activity of mammalian target of rapamycin (mTOR) with an IC₅₀ value of 708 nM. Oleocanthal inhibits the growth of several breast cancer cell lines at low micromolar concentration in a dose-dependent manner. Oleocanthal treatment caused a marked downregulation of phosphorylated mTOR in metastatic breast cancer cell line (MDA-MB-231). These results strongly indicate that mTOR inhibition is at least one of the factors of the reported anticancer and neuroprotective properties of oleocanthal.